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    Nat Struct Biol. 1995 Sep;2(9):740-4.

    Proposed structure of the A domains of factor VIII by homology modelling.

    Pan Y, DeFay T, Gitschier J, Cohen FE.

    We have predicted a structure for the three A domains of blood coagulation factor VIII by virtue of their homology to blue copper-binding proteins. This structure, consisting of six beta-barrels, is arranged in a triangular configuration with a single type II copper-binding site linking the A1 and A3 domains.

    PMID: 7552743 [PubMed - indexed for MEDLINE]

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