Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Genet Dev. 1995 Jun;5(3):335-41.

Novel approaches to linkage mapping.

Author information

  • 1Department of Pediatrics, University of Iowa, Iowa City 52242, USA.


The recent progress seen in the development of high-quality genetic markers and high-density human genetic maps is facilitating new strategies for mapping disease-causing and disease-susceptibility genes. These strategies, which include homozygosity mapping, DNA pooling, and the utilization of linkage disequilibrium, have been successfully applied to the mapping and fine mapping of several loci causing diseases segregating in genetically isolated populations.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk