Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain

Biochim Biophys Acta. 1994 Aug 2;1218(3):425-8. doi: 10.1016/0167-4781(94)90197-x.

Abstract

Ribosomal protein L37 mRNA is overexpressed in colon cancer. The nucleotide sequences of human L37 from several tumor and normal, colon and liver cDNA sources were determined to be identical. L37 mRNA was approximately 375 nucleotides long encoding 97 amino acids with M(r) = 11,070, pI = 12.6, multiple potential serine/threonine phosphorylation sites and a zinc-finger domain. The human sequence is compared to other species.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Blotting, Northern
  • Colon / metabolism
  • Colonic Neoplasms / metabolism
  • DNA Primers
  • DNA, Complementary / metabolism
  • Gene Expression
  • Humans
  • Liver / metabolism
  • Molecular Sequence Data
  • Neoplasms / metabolism
  • Phosphorylation
  • Polymerase Chain Reaction
  • RNA, Messenger / biosynthesis
  • RNA, Neoplasm / metabolism
  • Ribosomal Proteins / biosynthesis
  • Ribosomal Proteins / genetics*
  • Sequence Homology, Amino Acid
  • Serine
  • Threonine
  • Zinc Fingers

Substances

  • DNA Primers
  • DNA, Complementary
  • RNA, Messenger
  • RNA, Neoplasm
  • RPL37 protein, human
  • Ribosomal Proteins
  • Threonine
  • Serine

Associated data

  • GENBANK/L11567