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Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):54-6.

Regulation of development, survival and neoplastic growth of mast cells through the c-kit receptor.

Author information

  • 1Department of Pathology, Osaka University Medical School, Japan.

Abstract

Signaling through the c-kit receptor tyrosine kinase (Kit) is essential for development and survival of mast cells but not of basophils. Moreover, we recently found an activation mutation of Kit in several tumor mast cell lines.

PMID:
7542102
[PubMed - indexed for MEDLINE]
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