Biochem Biophys Res Commun. 1995 Apr 6;209(1):316-21.

Mast cell chemotactic activity of RANTES.

Mattoli S, Ackerman V, Vittori E, Marini M.

Source

Institute of Experimental Medicine, Milano, Italy.

Abstract

RANTES is a cytokine produced by activated T-lymphocytes that has been shown to exert chemotactic activity for memory-type CD4 T-lymphocytes and eosinophils. In this study, RANTES caused directional migration of human mast cells. When compared to other potential chemoattractants of the same cells, RANTES was found to be more potent than fibronectin and the c-kit receptor ligand, on a molar basis. This cytokine may be a common mechanism in allergic reactions which culminate in the selective migration of memory CD4 T-lymphocytes, eosinophils and mast cells at the tissue site. Asthma and allergic rhinitis may represent possible clinical examples.

PMID:: 7537040; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Supplemental Content

Related citations

Stem cell factor is a chemotactic factor for human mast cells. [J Immunol. 1994]
Stem cell factor is a chemotactic factor for human mast cells.
Nilsson G, Butterfield JH, Nilsson K, Siegbahn A. J Immunol. 1994 Oct 15; 153(8):3717-23.
Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils. [J Exp Med. 1992]
Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils.
Kameyoshi Y, Dörschner A, Mallet AI, Christophers E, Schröder JM. J Exp Med. 1992 Aug 1; 176(2):587-92.
Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities. [J Immunol. 2006]
Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.
Pang L, Nie M, Corbett L, Sutcliffe A, Knox AJ. J Immunol. 2006 Mar 15; 176(6):3788-95.
Review [The role of chemokines such as RANTES in allergic disease]. [Rinsho Byori. 1998]
Review [The role of chemokines such as RANTES in allergic disease].
Chihara J. Rinsho Byori. 1998 Aug; 46(8):816-20.
Review The role of human mast cell-derived cytokines in eosinophil biology. [J Interferon Cytokine Res. 2004]
Review The role of human mast cell-derived cytokines in eosinophil biology.
Shakoory B, Fitzgerald SM, Lee SA, Chi DS, Krishnaswamy G. J Interferon Cytokine Res. 2004 May; 24(5):271-81.

See reviews... See all...

Cited by 1 PubMed Central article

Review Allergen-induced generation of mediators in the mucosa. [Environ Health Perspect. 2001]
Review Allergen-induced generation of mediators in the mucosa.
Mattoli S. Environ Health Perspect. 2001 Aug; 109 Suppl 4:553-7.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Mast cell chemotactic activity of RANTES.
Mast cell chemotactic activity of RANTES.
Biochem Biophys Res Commun. 1995 Apr 6 ;209(1):316-21.

PubMed
Osseous choristoma of oral cavity--report of two cases and review of the literat...
Osseous choristoma of oral cavity--report of two cases and review of the literature.
Kaohsiung J Med Sci. 1998 Nov ;14(11):727-33.

PubMed
HIV vaccines: where we are and where we are going.
HIV vaccines: where we are and where we are going.
Lancet. 1996 Oct 5 ;348(9032):933-7.

PubMed
Effects of halothane on high affinity agonist binding and guanine nucleotide sen...
Effects of halothane on high affinity agonist binding and guanine nucleotide sensitivity of muscarinic acetylcholine receptors from brainstem of rat.
Neuropharmacology. 1987 Aug ;26(8):1201-5.

PubMed
Evidence that a benzodiazepine receptor mechanism regulates the secretion of pit...
Evidence that a benzodiazepine receptor mechanism regulates the secretion of pituitary beta-endorphin in rats.
Endocrinology. 1985 Aug ;117(2):474-80.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: