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J Virol. 1995 May;69(5):3237-9.

Echovirus 1 interaction with the isolated VLA-2 I domain.

Author information

  • 1Laboratory of Infectious Diseases, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

Erratum in

  • J Virol 1995 Jun;69(6):3965.

Abstract

The isolated I domain of the integrin VLA-2, produced as a bacterial fusion protein, specifically bound echovirus 1 and prevented virus attachment to cells. These results demonstrate that the receptor structures critical for virus attachment are contained solely within the VLA-2 I domain and that soluble receptor fragments are capable of preventing infection.

PMID:
7535868
[PubMed - indexed for MEDLINE]
PMCID:
PMC189033
Free PMC Article
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