Nihon Rinsho. 1994 Dec;52(12):3177-83.

[LDL-receptor-related protein].

[Article in Japanese]

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Third Department of Internal Medicine, University of Tokyo.

Abstract

The LDL-receptor-related protein is a multifunctional endocytotic receptor that clear apo E- and/or lipoprotein lipase-enriched lipoproteins, proteases such as alpha 2-macroglobulin plasminogen and activator inhibitor-1 (PAI-1), Pseudomonas exotoxin A and probably vitellogenin from blood circulation. Its role in plasma chylomicron remnant clearance has been postulated, and recently has been demonstrated by using its inhibitor; receptor-associated protein (RAP) in LDL receptor knockout mice.

PMID:: 7531787; [PubMed - indexed for MEDLINE]

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Molecular dissection of ligand binding sites on the low density lipoprotein receptor-related protein. [J Biol Chem. 1994]
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