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    Cytogenet Cell Genet. 1995;68(1-2):45-8.

    Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISH.

    Source

    Department of Cytogenetics, Tokyo Medical and Dental University, Japan.

    Abstract

    The human AQP2 (collecting duct water channel, aquaporin 2) gene encodes a 271 amino acid protein and is a member of the MIP (major intrinsic protein of lens fiber) gene family. Using two-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for AQP2 and MIP as probes, we found that both genes mapped closely within the human chromosome region 12q13.

    PMID:
    7525161
    [PubMed - indexed for MEDLINE]

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