Your browser version may not work well with NCBI's Web applications. More information here...
1: Int J Radiat Oncol Biol Phys. 1994 Jul 30;29(5):1011-4.Links

Retreatment with radiotherapy for painful bone metastases.

Mithal NP, Needham PR, Hoskin PJ.

Department of Radiotherapy and Oncology, Royal London Hospital, Whitechapel.

PURPOSE: To evaluate the response to reirradiation of painful bone metastases following initial treatment with radiotherapy. METHODS AND MATERIALS: A retrospective analysis of 105 consecutive patients treated with palliative radiotherapy for painful bone metastases. A total of 280 individual treatment sites were identified, of which 57 were retreated once and 8 were retreated twice. RESULTS: The overall response rate to initial treatment was 84% for pain relief, and at first retreatment this was 87%. Seven of eight patients retreated a second time also achieved pain relief. No relation to radiation dose, primary tumor type, or site was seen. CONCLUSIONS: In patients relapsing after radiotherapy to painful bone metastases who have responded initially, reirradiation can be recommended with a similar probability of response.

PMID: 7521863 [PubMed - indexed for MEDLINE]