Cytogenet Cell Genet. 1994;66(4):260-2.

Assignment of the human gene for the water channel of renal collecting duct Aquaporin 2 (AQP2) to chromosome 12 region q12-->q13.

Deen PM, Weghuis DO, Sinke RJ, Geurts van Kessel A, Wieringa B, van Os CH.

Source

Department of Physiology, University of Nijmegen, The Netherlands.

Abstract

The chromosomal localization of the gene encoding Aquaporin 2 (previously called WCH-CD), which acts as a water channel in the collecting tubules of the kidney, was determined. Southern blot hybridizations of chromosomal DNA from a panel of 25 different human-rodent hybrid cell lines assigned AQP2 to the q-arm of human chromosome 12. Additionally, in situ hybridization on R-banded metaphase chromosomes localized AQP2 to the q12-->q13 region of this chromosome.

PMID:: 7512890; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Medical

Supplemental Content

Save items

Related citations in PubMed

The human gene for water channel aquaporin 1 (AQP1) is localized on chromosome 7p15-->p14. [Cytogenet Cell Genet. 1994]
The human gene for water channel aquaporin 1 (AQP1) is localized on chromosome 7p15-->p14.
Deen PM, Weghuis DO, Geurs van Kessel A, Wieringa B, van Os CH. Cytogenet Cell Genet. 1994; 65(4):243-6.
Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISH. [Cytogenet Cell Genet. 1995]
Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISH.
Saito F, Sasaki S, Chepelinsky AB, Fushimi K, Marumo F, Ikeuchi T. Cytogenet Cell Genet. 1995; 68(1-2):45-8.
Localization of the human gene for aquaporin 3 (AQP3) to chromosome 9, region p21-->p12, using fluorescent in situ hybridization. [Cytogenet Cell Genet. 1996]
Localization of the human gene for aquaporin 3 (AQP3) to chromosome 9, region p21-->p12, using fluorescent in situ hybridization.
Mulders SM, Olde Weghuis D, van Boxtel JA, van Kessel AG, Echevarria M, van Os CH, Deen PM. Cytogenet Cell Genet. 1996; 72(4):303-5.
Review Discovery of aquaporins: a breakthrough in research on renal water transport. [Pediatr Nephrol. 1995]
Review Discovery of aquaporins: a breakthrough in research on renal water transport.
van Lieburg AF, Knoers NV, Deen PM. Pediatr Nephrol. 1995 Apr; 9(2):228-34.
Review Renal aquaporins. [Kidney Int. 1996]
Review Renal aquaporins.
Knepper MA, Wade JB, Terris J, Ecelbarger CA, Marples D, Mandon B, Chou CL, Kishore BK, Nielsen S. Kidney Int. 1996 Jun; 49(6):1712-7.

See reviews... See all...

Cited by 2 PubMed Central articles

The genetics of primary nocturnal enuresis: inheritance and suggestion of a second major gene on chromosome 12q. [J Med Genet. 1997]
The genetics of primary nocturnal enuresis: inheritance and suggestion of a second major gene on chromosome 12q.
Arnell H, Hjälmås K, Jägervall M, Läckgren G, Stenberg A, Bengtsson B, Wassén C, Emahazion T, Annerén G, Pettersson U, et al. J Med Genet. 1997 May; 34(5):360-5.
Patients with autosomal nephrogenic diabetes insipidus homozygous for mutations in the aquaporin 2 water-channel gene. [Am J Hum Genet. 1994]
Patients with autosomal nephrogenic diabetes insipidus homozygous for mutations in the aquaporin 2 water-channel gene.
van Lieburg AF, Verdijk MA, Knoers VV, van Essen AJ, Proesmans W, Mallmann R, Monnens LA, van Oost BA, van Os CH, Deen PM. Am J Hum Genet. 1994 Oct; 55(4):648-52.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide
Primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Assignment of the human gene for the water channel of renal collecting duct Aqua...
Assignment of the human gene for the water channel of renal collecting duct Aquaporin 2 (AQP2) to chromosome 12 region q12-->q13.
Cytogenet Cell Genet. 1994 ;66(4):260-2.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Assignment of the human gene for the water channel of renal collecting duct Aquaporin 2 (AQP2) to chromosome 12 region q12-->q13.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 2 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information