Arch Pathol Lab Med. 1995 Dec;119(12):1164-7.

Primary adrenal leiomyosarcoma in a man with acquired immunodeficiency syndrome (AIDS). Further evidence for an increase in smooth muscle tumors related to Epstein-Barr infection in AIDS.

Zetler PJ, Filipenko JD, Bilbey JH, Schmidt N.

Source

Department of Pathology and Laboratory Medicine, St Paul's Hospital, University of British Columbia, Vancouver, Canada.

Abstract

We report a rare primary adrenal leiomyosarcoma in a 30-year-old, human immunodeficiency virus--positive man. This is, we believe, the third documented case in the English literature of this tumor in this site, and the first to be reported in an adult male with acquired immunodeficiency syndrome. The smooth muscle origin of this tumor was apparent by routine microscopy and confirmed by positive immunostaining for smooth muscle actin. The patient is presently well and shows no evidence of recurrence 20 months after surgery. The present findings are discussed with reference to the reported rising incidence of smooth muscle tumors in human immunodeficiency virus--infected patients and the associated etiologic role of Epstein-Barr virus in the pathogenesis of these tumors.

Comment in

Arch Pathol Lab Med. 1996 Sep;120(9):797-8.

PMID:: 7503667; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

RNA, Messenger

LinkOut - more resources

Medical

Supplemental Content

Save items

Related citations in PubMed

Multicentric endobronchial smooth muscle tumors associated with the Epstein-Barr virus in an adult patient with the acquired immunodeficiency syndrome: a case report. [Cancer. 1997]
Multicentric endobronchial smooth muscle tumors associated with the Epstein-Barr virus in an adult patient with the acquired immunodeficiency syndrome: a case report.
Bluhm JM, Yi ES, Diaz G, Colby TV, Colt HG. Cancer. 1997 Nov 15; 80(10):1910-3.
Latent Epstein-Barr virus infection demonstrated in low-grade leiomyosarcomas of adults with acquired immunodeficiency syndrome, but not in adjacent Kaposi's lesion or smooth muscle tumors in immunocompetent patients. [Arch Pathol Lab Med. 1997]
Latent Epstein-Barr virus infection demonstrated in low-grade leiomyosarcomas of adults with acquired immunodeficiency syndrome, but not in adjacent Kaposi's lesion or smooth muscle tumors in immunocompetent patients.
Boman F, Gultekin H, Dickman PS. Arch Pathol Lab Med. 1997 Aug; 121(8):834-8.
Review Primary meningeal Epstein-Barr virus-related leiomyosarcoma in a man infected with human immunodeficiency virus: review of literature, emphasizing the differential diagnosis and pathogenesis. [Appl Immunohistochem Mol Morph...]
Review Primary meningeal Epstein-Barr virus-related leiomyosarcoma in a man infected with human immunodeficiency virus: review of literature, emphasizing the differential diagnosis and pathogenesis.
Zevallos-Giampietri EA, Yañes HH, Orrego Puelles J, Barrionuevo C. Appl Immunohistochem Mol Morphol. 2004 Dec; 12(4):387-91.
Splenic smooth-muscle tumors in children with acquired immunodeficiency syndrome: report of two cases of this unusual location with evidence of an association with Epstein-Barr virus. [Virchows Arch. 2000]
Splenic smooth-muscle tumors in children with acquired immunodeficiency syndrome: report of two cases of this unusual location with evidence of an association with Epstein-Barr virus.
Barbashina V, Heller DS, Hameed M, Albanese E, Goldstein M, Dashefsky B, Dieudonne A, Chakraborty R. Virchows Arch. 2000 Feb; 436(2):138-9.
Review Epstein-Barr virus-associated multicentric leiomyosarcoma in an adult patient after heart transplantation: case report and review of the literature. [Am J Surg Pathol. 2000]
Review Epstein-Barr virus-associated multicentric leiomyosarcoma in an adult patient after heart transplantation: case report and review of the literature.
Rogatsch H, Bonatti H, Menet A, Larcher C, Feichtinger H, Dirnhofer S. Am J Surg Pathol. 2000 Apr; 24(4):614-21.

See reviews... See all...

Cited by 5 PubMed Central articles

Primary adrenal leiomyosarcoma: a case report and literature review. [Clin Med Oncol. 2008]
Primary adrenal leiomyosarcoma: a case report and literature review.
M M, M B, M T, M V. Clin Med Oncol. 2008; 2:353-6. Epub 2008 Apr 28.
AIDS-Related EBV-Associated Smooth Muscle Tumors: A Review of 64 Published Cases. [Patholog Res Int. 2011]
AIDS-Related EBV-Associated Smooth Muscle Tumors: A Review of 64 Published Cases.
Purgina B, Rao UN, Miettinen M, Pantanowitz L. Patholog Res Int. 2011 Mar 10; 2011:561548. Epub 2011 Mar 10.
Primary leiomyosarcoma of the adrenal gland. [Sarcoma. 2001]
Primary leiomyosarcoma of the adrenal gland.
Etten B, van Ijken MG, Mooi WJ, Oudkerk M, van Geel AN. Sarcoma. 2001; 5(2):95-9.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Primary adrenal leiomyosarcoma in a man with acquired immunodeficiency syndrome ...
Primary adrenal leiomyosarcoma in a man with acquired immunodeficiency syndrome (AIDS). Further evidence for an increase in smooth muscle tumors related to Epstein-Barr infection in AIDS.
Arch Pathol Lab Med. 1995 Dec ;119(12):1164-7.

PubMed
Aicardi syndrome with multiple tumors: a case report with literature review.
Aicardi syndrome with multiple tumors: a case report with literature review.
Brain Dev. 1995 Jul-Aug ;17(4):283-5.

PubMed
The effects of sleep deprivation on the circadian rhythm of plasma cortisol leve...
The effects of sleep deprivation on the circadian rhythm of plasma cortisol levels in depressive patients.
Folia Psychiatr Neurol Jpn. 1978 ;32(4):479-87.

PubMed
Involvement of collagenous spherulosis by lobular carcinoma in situ. Potential c...
Involvement of collagenous spherulosis by lobular carcinoma in situ. Potential confusion with cribriform ductal carcinoma in situ.
Am J Surg Pathol. 1995 Dec ;19(12):1366-70.

PubMed
Radiographic assessment for patients with low back pain.
Radiographic assessment for patients with low back pain.
Spine (Phila Pa 1976). 1995 Aug 15 ;20(16):1839-41.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: