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    Virchows Arch A Pathol Anat Histol. 1980;387(1):67-80.

    Secondary athrocytotic cardiomyopathy--heart damage due to Wilson's disease.

    Kaduk B, Metze K, Schmidt PF, Brandt G.

    Post-mortem atomic absorption spectrophotometry of the myocardium of a 14-year-old boy revealed a hundred-fold increase in copper. Further electrolyte analysis of the myocardium showed changes corresponding to metabolic heart muscle damage. Ultrastructural examination showed all the feature of a cardiomyopathy at the cellular level. Laser-Microprobe-Mass-Analysis demonstrated an inhomogeneous distribution of copper. An essential factor in the mechanism of death is heart damage.

    PMID: 7467117 [PubMed - indexed for MEDLINE]

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