Abstract
Two cases of xeroderma pigmentosum were studied at the cytogenetic and molecular level. DNA repair impairment was revealed in case 1 by a nucleoid sedimentation technique whereas a half diminished rate of DNA repair could be demonstrated in case 2. This may be a further case of a xeroderma pigmentosum variant.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Child, Preschool
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DNA Repair / radiation effects
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Humans
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Karyotyping
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Lymphocytes / radiation effects
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Male
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Mitosis / radiation effects
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Neoplasms, Radiation-Induced / diagnosis*
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Skin Neoplasms / diagnosis*
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Skin Neoplasms / genetics
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Ultraviolet Rays / adverse effects
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Xeroderma Pigmentosum / diagnosis*
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Xeroderma Pigmentosum / genetics