Tissue Antigens. 1981 Nov;18(5):356-63.

Measuring the strength of associations between HLA antigens and diseases.

Abstract

The strength of the population association between an antigen and a disease can be estimated not only by the relative risk value, but also by what variously has been called the population attributable risk and the etiologic fraction. This alternative measure has certain advantages if the association is due to linkage disequilibrium between the antigen allele and a "disease" allele at a closely linked "disease susceptibility" locus. In particular, it can then be used to determine which of many antigens associated with the same disease has the strongest association from a genetical point of view.

PMID:: 7344182; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

HLA Antigens

Grant Support

LinkOut - more resources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

Statistical aspects of measuring the strength of associations between HLA antigens and diseases. [Tissue Antigens. 1983]
Statistical aspects of measuring the strength of associations between HLA antigens and diseases.
Thomson G, Motro U, Selvin S. Tissue Antigens. 1983 Apr; 21(4):320-8.
The human histocompatibility system: anthropological considerations. [Am J Phys Anthropol. 1983]
The human histocompatibility system: anthropological considerations.
Thomson G. Am J Phys Anthropol. 1983 Sep; 62(1):81-9.
Effect of human leukocyte antigen heterozygosity on infectious disease outcome: the need for allele-specific measures. [BMC Med Genet. 2003]
Effect of human leukocyte antigen heterozygosity on infectious disease outcome: the need for allele-specific measures.
Lipsitch M, Bergstrom CT, Antia R. BMC Med Genet. 2003 Jan 24; 4:2. Epub 2003 Jan 24.
Review Genetic susceptibility factors of Type 1 diabetes in Asians. [Diabetes Metab Res Rev. 2001]
Review Genetic susceptibility factors of Type 1 diabetes in Asians.
Park Y, Eisenbarth GS. Diabetes Metab Res Rev. 2001 Jan-Feb; 17(1):2-11.
Review HLA and disease associations: detecting the strongest association. [Tissue Antigens. 1994]
Review HLA and disease associations: detecting the strongest association.
Svejgaard A, Ryder LP. Tissue Antigens. 1994 Jan; 43(1):18-27.

See reviews... See all...

Cited by 32 PubMed Central articles

Haplotype Diversity and Reconstruction of Ancestral Haplotype Associated with the c.35delG Mutation in the GJB2 (Cx26) Gene among the Volgo-Ural Populations of Russia. [Acta Naturae. 2011]
Haplotype Diversity and Reconstruction of Ancestral Haplotype Associated with the c.35delG Mutation in the GJB2 (Cx26) Gene among the Volgo-Ural Populations of Russia.
Dzhemileva LU, Posukh OL, Barashkov NA, Fedorova SA, Teryutin FM, Akhmetova VL, Khidiyatova IM, Khusainova RI, Lobov SL, Khusnutdinova EK. Acta Naturae. 2011 Jul; 3(3):52-63.
MHC polymorphism and disease resistance to Vibrio anguillarum in 8 families of half-smooth tongue sole (Cynoglossus semilaevis). [BMC Genet. 2011]
MHC polymorphism and disease resistance to Vibrio anguillarum in 8 families of half-smooth tongue sole (Cynoglossus semilaevis).
Du M, Chen SL, Liu YH, Liu Y, Yang JF. BMC Genet. 2011 Sep 2; 12:78. Epub 2011 Sep 2.
The USH2A c.2299delG mutation: dating its common origin in a Southern European population. [Eur J Hum Genet. 2010]
The USH2A c.2299delG mutation: dating its common origin in a Southern European population.
Aller E, Larrieu L, Jaijo T, Baux D, Espinós C, González-Candelas F, Nájera C, Palau F, Claustres M, Roux AF, et al. Eur J Hum Genet. 2010 Jul; 18(7):788-93. Epub 2010 Feb 10.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Measuring the strength of associations between HLA antigens and diseases.
Measuring the strength of associations between HLA antigens and diseases.
Tissue Antigens. 1981 Nov ;18(5):356-63.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: