In 8 patients (4 males, 4 females, at the age from 23 to 64 years) with a since 2 to 32 years existing generalised psoriasis vulgaris of pure plaque type a treatment with peritoneal dialysis was performed over a period of 1-6 months with on an average 18 treatment days. A full remission of the changes did not appear in any case, only in one patient a transitory involution of the skin changes and of the arthropathy could be established. In 5 patients the picture of the disease remained uninfluenced, 2 showed a deterioration. Wether this failure of the treatment is conditioned by an inadequate, too little intensive treatment, must, in comparison to the reports of literature, be regarded as little probable. By reason of our results the treatment with peritoneal dialysis according to the scheme mentioned cannot be recommended.