Am J Psychiatry. 1981 Dec;138(12):1624-5.

Induction of rapid mood cycling during L-dopa treatment in a bipolar patient.

Abstract

The authors report a longitudinal case study of a woman with a history of bipolar affective disorder in which L-dopa shortened the manic-depressive cycle length when administered in a double-blind trial. This finding suggests a dopaminergic mechanism specifically in changing the frequency of cycling between depression and mania.

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Review [Antipsychotics in bipolar disorders]. [Encephale. 2004]
Review [Antipsychotics in bipolar disorders].
Vacheron-Trystram MN, Braitman A, Cheref S, Auffray L. Encephale. 2004 Sep-Oct; 30(5):417-24.
Induction of mania by L-dopa in a nonbipolar patient. [J Clin Psychopharmacol. 1985]
Induction of mania by L-dopa in a nonbipolar patient.
Harsch HH, Miller M, Young LD. J Clin Psychopharmacol. 1985 Dec; 5(6):338-9.
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Suppes T, Brown E, Schuh LM, Baker RW, Tohen M. J Affect Disord. 2005 Dec; 89(1-3):69-77. Epub 2005 Oct 25.
Review Antidepressant-induced rapid cycling: another perspective. [Ann Clin Psychiatry. 2006]
Review Antidepressant-induced rapid cycling: another perspective.
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Induction of rapid mood cycling during L-dopa treatment in a bipolar patient.
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Induction of rapid mood cycling during L-dopa treatment in a bipolar patient.

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