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Fourteen men were studied over a period of 10 years before and after bilateral was ligation. Seven men (50%) continued to have demonstrable circulating sperm-agglutinating antibodies, and one man had persistent sperm-immobilizing antibodies at a low titer of 1:2. None of the 10 ejaculates submitted contained spermatozoa or antibody activity, although two of the seminal plasma specimens immediately immobilized donor spermatozoa upon contact. There were no adverse medical reactions or conditions noted in these men during the course of the study.
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