Laryngol Rhinol Otol (Stuttg). 1978 Nov;57(11):997-1007.

[Betahistine treatment of Menière's disease (author's transl)].

[Article in German]

Abstract

An evaluation of Betahistine hydrochloride treatment of 92 patients suffering from Menière disease and Menière-like syndrom is presented. Observed for more than one year 54 (89%) patients showed complete relief of vertigo-attack symptoms. 7 (12%) patients showed a distinct improvement in their hearing as reflected in their audiograms, only 7 (12%) patients showed a further loss of hearing. There appeared to be a trend toward further improvement when therapy was maintained over at least a period of 3--4 month. Vertigo seemed to be the symptom most responsive to treatment and tinnitus the most resistant. Minimal side effects were observed in 17 (18%) patients.

PMID:: 723406; [PubMed - indexed for MEDLINE]

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Betahistine hydrochloride in Méniére's disease. [Postgrad Med J. 1976]
Betahistine hydrochloride in Méniére's disease.
Frew IJ, Menon GN. Postgrad Med J. 1976 Aug; 52(610):501-3.
[Treatment of Menière's disease with betahistine (author's transl)]. [HNO. 1976]
[Treatment of Menière's disease with betahistine (author's transl)].
Stupp H, Kahl S. HNO. 1976 Sep; 24(9):320-5.
Clinical trials of betahistine hydrochloride in the treatment of Ménière's disease. [Acta Otorhinolaryngol Belg. 1975]
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Segers JM, Boedts D. Acta Otorhinolaryngol Belg. 1975; 29(5):814-21.
Review Betahistine for Menière's disease or syndrome. [Cochrane Database Syst Rev. 2001]
Review Betahistine for Menière's disease or syndrome.
James AL, Burton MJ. Cochrane Database Syst Rev. 2001; (1):CD001873.
Review Histamine in the treatment of vertigo. [Acta Otolaryngol Suppl. 1991]
Review Histamine in the treatment of vertigo.
Fischer AJ. Acta Otolaryngol Suppl. 1991; 479:24-8.

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