Genetic effects of formaldehyde in the mouse

Mutat Res. 1981 Jan;88(1):109-14. doi: 10.1016/0165-1218(81)90095-1.

Abstract

A chromosomal analysis of spermatocytes at metaphase I failed to reveal any chromosomal lesions during spermatogenesis of mice treated with formaldehyde. Similarly, the dominant lethal test, except during the first and third weeks, showed no detectable effect.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Aberrations*
  • Chromosomes / drug effects*
  • Formaldehyde / pharmacology*
  • Genes, Dominant
  • Genes, Lethal
  • Male
  • Mice
  • Mutagenicity Tests
  • Spermatocytes / ultrastructure*
  • Spermatozoa / ultrastructure*

Substances

  • Formaldehyde