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Science. 1982 Apr 23;216(4544):436-7.

Heroin "overdose" death: contribution of drug-associated environmental cues.

Abstract

A model of "overdose" deaths among heroin addicts is proposed which emphasizes recent findings concerning the contribution of drug-associated environmental cues to drug tolerance. Results of animal experiments performed to evaluate this model suggest that conditioned drug-anticipatory responses, in addition to pharmacological factors, affect heroin-induced mortality.

PMID:
7200260
[PubMed - indexed for MEDLINE]
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