Science. 1980 Jan 18;207(4428):329-31.

Interchangeability of stress and amphetamine in sensitization.

Antelman SM, Eichler AJ, Black CA, Kocan D.

Abstract

In view of similarities between the behavioral, biochemical, and electrophysiological effects of amphetamine and stress, we tested the hypothesis that presentation of a stressor, mild tail pressure, can sensitize an animal to the later effects of amphetamine, and vice versa. Our findings supported this hypothesis and suggest that amphetamine and at least some stressors may be interchangeable in their ability to induce a sensitization. The data raise the possibility that stress might be a common variable contributing to both amphetamine psychosis and some forms of schizophrenia.

PMID:: 7188649; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, U.S. Gov't, P.H.S.

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Reduction of dopaminergic supersensitivity by a single dose of amphetamine. [Naunyn Schmiedebergs Arch Phar...]
Reduction of dopaminergic supersensitivity by a single dose of amphetamine.
Haracz JL, Tseng LF. Naunyn Schmiedebergs Arch Pharmacol. 1980 Aug; 313(2):131-3.
Atypical antipsychotic drugs block selective components of amphetamine-induced stereotypy. [Pharmacol Biochem Behav. 1988]
Atypical antipsychotic drugs block selective components of amphetamine-induced stereotypy.
Tschanz JT, Rebec GV. Pharmacol Biochem Behav. 1988 Nov; 31(3):519-22.
Dopaminergic mediation of the interoceptive cue produced by d-amphetamine in rats. [Psychopharmacologia. 1975]
Dopaminergic mediation of the interoceptive cue produced by d-amphetamine in rats.
Schechter MD, Cook PG. Psychopharmacologia. 1975 May 28; 42(2):185-93.
Review The effects of D-amphetamine on dopaminergic regulated mechanisms of physiological and behavioral thermoregulation. [Curr Dev Psychopharmacol. 1979]
Review The effects of D-amphetamine on dopaminergic regulated mechanisms of physiological and behavioral thermoregulation.
Yehuda S. Curr Dev Psychopharmacol. 1979; 5:125-71.
Review [Stress sensitization induced by stressor and methamphetamine]. [Nihon Shinkei Seishin Yakuriga...]
Review [Stress sensitization induced by stressor and methamphetamine].
Yui K, Ikemoto S. Nihon Shinkei Seishin Yakurigaku Zasshi. 2004 Jun; 24(3):151-7.

See reviews... See all...

Cited by 25 PubMed Central articles

Yohimbine-induced amygdala activation in pathological gamblers: a pilot study. [PLoS One. 2012]
Yohimbine-induced amygdala activation in pathological gamblers: a pilot study.
Elman I, Becerra L, Tschibelu E, Yamamoto R, George E, Borsook D. PLoS One. 2012; 7(2):e31118. Epub 2012 Feb 2.
Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats. [J Neurosci. 2011]
Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats.
Miczek KA, Nikulina EM, Shimamoto A, Covington HE 3rd. J Neurosci. 2011 Jul 6; 31(27):9848-57.
Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibility? [Psychopharmacology (Berl). 2011]
Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibility?
Datson NA, Speksnijder N, de Jong IE, Steenbergen PJ, Vielsted Christensen K, Potempa K, Torleif Pedersen J, Egebjerg J, Kallunki P, Nielsen EB, et al. Psychopharmacology (Berl). 2011 Oct; 217(4):525-38. Epub 2011 May 3.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Interchangeability of stress and amphetamine in sensitization.
Interchangeability of stress and amphetamine in sensitization.
Science. 1980 Jan 18 ;207(4428):329-31.

PubMed
Hemiplegia and peripheral gangrene secondary to large and medium size vessels in...
Hemiplegia and peripheral gangrene secondary to large and medium size vessels involvement in C.R.E.S.T. syndrome.
Clin Rheumatol. 1982 Dec ;1(4):295-9.

PubMed
Generalized equations for predicting body density of men.
Generalized equations for predicting body density of men.
Br J Nutr. 1978 Nov ;40(3):497-504.

PubMed
Diaphragmatic herniorrhaphy in a cow.
Diaphragmatic herniorrhaphy in a cow.
Mod Vet Pract. 1982 Sep ;63(9):743-4.

PubMed
Long-term effects of continuous exposure to p-chloroamphetamine on central serot...
Long-term effects of continuous exposure to p-chloroamphetamine on central serotonergic mechanisms in mice.
Biochem Pharmacol. 1978 ;27(16):2033-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: