Disturbances of sleep and cognitive functioning in patients with dementia

Neurobiol Aging. 1982 Winter;3(4):371-7. doi: 10.1016/0197-4580(82)90025-2.

Abstract

The relationship of sleep, circadian rhythms, and cognitive impairment in dementia patients is briefly reviewed. All-night sleep EEG data were collected in relatively young and relatively unimpaired patients with presumptive Alzheimer's disease and eight age-matched controls. Delta sleep time and Delta sleep % (Stages 3 and 4)--but not REM sleep measures--were significantly reduced in the patients. Implications of these findings are discussed.

MeSH terms

  • Aged
  • Alzheimer Disease / physiopathology*
  • Circadian Rhythm
  • Cognition Disorders / etiology*
  • Cognition Disorders / physiopathology
  • Dementia / physiopathology*
  • Electroencephalography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Sleep / physiology
  • Sleep Stages / physiology
  • Sleep Wake Disorders / etiology*
  • Sleep Wake Disorders / physiopathology
  • Sleep, REM / physiology