The disease is characterized by a painless tender and mainly worm-like lesion which partly or totally encircles the distal penis, proximal of the sulcus coronarius. Usually, there are no local or regional inflammatory signs of the glans, preputium, or the inguinal lymph nodes. The anatomic target is a lymphatic collecting vessel. The pathologic process is morphologically based on three major features: lymphostasis, coagulation thrombus formation, and vessel wall thickening. We therefore propose the term lymphangiofibrosis thrombotica occlusiva. Men 20-40 years of age are most commonly affected. A therapeutic measure is not necessary, unless there is no spontaneous regression which one can except in 90% of the patients within 2 months. Mechanical and unknown microbiologic insults are discussed as etiological factors. Furthermore, the topographical distribution of blood and lymphatic vessels of the distal penis region is delineated. Six patients are presented with the clinical data.