Evaluation of three preparations of etomidate

Br J Anaesth. 1978 Sep;50(9):925-9. doi: 10.1093/bja/50.9.925.

Abstract

Three formulations of etomidate were evaluated in unpremedicated patients undergoing minor gynaecological procedures. There was a high frequency of pain on injection (up to 50%) and excitatory phenomena (up to 95%) with all formulations. The frequency of excitatory phenomena was significantly greater than that after methohexitone. Recovery was rapid, but emetic sequelae were frequent and significantly more marked than after methohexitone.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Anesthesia, Intravenous / methods
  • Buffers
  • Etomidate / administration & dosage*
  • Etomidate / adverse effects
  • Female
  • Humans
  • Imidazoles / administration & dosage*
  • Polyethylene Glycols
  • Propylene Glycols
  • Solutions
  • Time Factors
  • Water

Substances

  • Buffers
  • Imidazoles
  • Propylene Glycols
  • Solutions
  • Water
  • Polyethylene Glycols
  • Etomidate