A comparison of acyclovir and idoxuridine as treatment for ulcerative herpetic keratitis

Br J Ophthalmol. 1980 Oct;64(10):763-5. doi: 10.1136/bjo.64.10.763.

Abstract

Sixty patients were treated with either acyclovir 2% ointment or idoxuridine 1% ointment 5 times a day in a stratified randomised double-blind clinical trial. The 2 antiviral agents were equally effective.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Acyclovir
  • Clinical Trials as Topic
  • Corneal Ulcer / drug therapy
  • Double-Blind Method
  • Guanine / analogs & derivatives*
  • Guanine / therapeutic use
  • Humans
  • Idoxuridine / therapeutic use*
  • Keratitis, Dendritic / drug therapy*
  • Male
  • Ointments
  • Random Allocation

Substances

  • Ointments
  • Guanine
  • Idoxuridine
  • Acyclovir