Format

Send to:

Choose Destination
See comment in PubMed Commons below
Br Med J. 1980 Mar 29;280(6218):885-8.

Randomised trial comparing propranolol with atenolol in immediate treatment of suspected myocardial infarction.

Abstract

The value of beta-blockade for suspected acute myocardial infarction was assessed by determining the six-week and one-year mortality rates in patients started on propranolol, atenolol, or placebo immediately on entry to a coronary care unit. A total of 388 patients entered this double-blind, randomised study, and when analysed on the basis of the initial, intention-to-treat categories there was no significant difference between the three groups in respect of the mortality rate at one year. There was, however, a high withdrawal rate from the trial; the reasons for this illustrate problems of physician compliance and interpretation of data, which are common to all early-entry trials of haemodynamically active agents in acute myocardial infarction.

PMID:
6992916
[PubMed - indexed for MEDLINE]
PMCID:
PMC1601074
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk