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Nature. 1980 Jan 10;283(5743):139-46.

The pathogenesis of cancer metastasis.

Abstract

Metastases do not result from random survival of cells released from the primary tumour but from the selective growth of specialised subpopulations of highly metastatic cells endowed with specific properties that befit them to complete each step of the metastatic process.

PMID:
6985715
[PubMed - indexed for MEDLINE]
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