J Nerv Ment Dis. 1978 Sep;166(9):663-5.

Multiple sclerosis masquerading as lithium toxicity.

Abstract

The author presents a case report of a manic-depressive patient who developed dysarthria and ataxia while on lithium maintenance. These symptoms were erroneously attributed to lithium toxicity occurring at therapeutic serum levels. However, the symptoms persisted despite diminution in lithium dosage and a neurological consultation revealed the diagnosis of multiple sclerosis. The author concludes that lithium therapy is effective with manic-depressive patients, that adverse side effects are infrequent and can occur at toxic or therapeutic serum lithium levels, and that the exceptional patient may have a second illness incorrectly attributed to lithium toxicity.

PMID:: 690625; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

Lithium

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Review [Antipsychotics in bipolar disorders]. [Encephale. 2004]
Review [Antipsychotics in bipolar disorders].
Vacheron-Trystram MN, Braitman A, Cheref S, Auffray L. Encephale. 2004 Sep-Oct; 30(5):417-24.
Persistent dysarthria with apraxia associated with a combination of lithium carbonate and haloperidol. [J Clin Psychiatry. 1982]
Persistent dysarthria with apraxia associated with a combination of lithium carbonate and haloperidol.
Bond WS, Carvalho M, Foulks EF. J Clin Psychiatry. 1982 Jun; 43(6):256-7.
Review A systematic review and economic model of the clinical effectiveness and cost-effectiveness of interventions for preventing relapse in people with bipolar disorder. [Health Technol Assess. 2007]
Review A systematic review and economic model of the clinical effectiveness and cost-effectiveness of interventions for preventing relapse in people with bipolar disorder.
Soares-Weiser K, Bravo Vergel Y, Beynon S, Dunn G, Barbieri M, Duffy S, Geddes J, Gilbody S, Palmer S, Woolacott N. Health Technol Assess. 2007 Oct; 11(39):iii-iv, ix-206.
Unrecognized chronic lithium neurotoxic reactions. [JAMA. 1983]
Unrecognized chronic lithium neurotoxic reactions.
Lewis DA. JAMA. 1983 Oct 21; 250(15):2029-30.
Differential efficacy of olanzapine and lithium in preventing manic or mixed recurrence in patients with bipolar I disorder based on number of previous manic or mixed episodes. [J Clin Psychiatry. 2006]
Differential efficacy of olanzapine and lithium in preventing manic or mixed recurrence in patients with bipolar I disorder based on number of previous manic or mixed episodes.
Ketter TA, Houston JP, Adams DH, Risser RC, Meyers AL, Williamson DJ, Tohen M. J Clin Psychiatry. 2006 Jan; 67(1):95-101.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Multiple sclerosis masquerading as lithium toxicity.
Multiple sclerosis masquerading as lithium toxicity.
J Nerv Ment Dis. 1978 Sep ;166(9):663-5.

PubMed
Herbicidal treatments for control of Papaver somniferum L.
Herbicidal treatments for control of Papaver somniferum L.
Bull Narc. 1980 ;32(1):33-43.

PubMed
In vitro responses of the epidermis to triiodothyronine.
In vitro responses of the epidermis to triiodothyronine.
J Invest Dermatol. 1978 Sep ;71(3):202-4.

PubMed
Liposarcoma of the foot: a case report.
Liposarcoma of the foot: a case report.
J Foot Surg. 1978 Spring ;17(1):27-31.

PubMed
Trichotillomania and trichobezoar in an infant. Psychological factors underlying...
Trichotillomania and trichobezoar in an infant. Psychological factors underlying this symptom.
J Am Acad Child Psychiatry. 1978 Summer ;17(3):533-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Multiple sclerosis masquerading as lithium toxicity.

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information