Immunol Commun. 1980;9(5):453-63.

The hemolytic equivalence of human, guinea pig and canine complement proteins.

Abstract

The ability of functionally pure human, guinea pig and canine complement proteins to fulfill the hemolytic function of a substituted analagous component in an otherwise totally homogeneous complement sequence was investigated by means of conventional hemolytic assays. A striking feature was the observation that for hemolysis to occur, differing requirements for enzyme-substrate homology were exhibited by each of the three species of C3 and C5 convertases (C3 and C5 CVA). The results suggest that different strategies of molecular interaction evolved in complement systems of different species.

PMID:: 6903556; [PubMed - indexed for MEDLINE]

Supplemental Content

Save items

Related citations in PubMed

Activation of the fifth and sixth component of the complement system: similarities between C5b6 and C(56)a with respect to lytic enhancement by cell-bound C3b or A2C, and species preferences of target cell. [J Immunol. 1981]
Activation of the fifth and sixth component of the complement system: similarities between C5b6 and C(56)a with respect to lytic enhancement by cell-bound C3b or A2C, and species preferences of target cell.
Hänsch GM, Hammer CH, Mayer MM, Shin ML. J Immunol. 1981 Sep; 127(3):999-1002.
Membrane factors responsible for homologous species restriction of complement-mediated lysis: evidence for a factor other than DAF operating at the stage of C8 and C9. [J Immunol. 1986]
Membrane factors responsible for homologous species restriction of complement-mediated lysis: evidence for a factor other than DAF operating at the stage of C8 and C9.
Shin ML, Hänsch G, Hu VW, Nicholson-Weller A. J Immunol. 1986 Mar 1; 136(5):1777-82.
Complement lysis of human erythrocytes. III. Differing effectiveness of human and guinea pig C9 on normal and paroxysmal nocturnal hemoglobinuria cells. [J Immunol. 1980]
Complement lysis of human erythrocytes. III. Differing effectiveness of human and guinea pig C9 on normal and paroxysmal nocturnal hemoglobinuria cells.
Rosenfeld SI, Packman CH, Jenkins DE Jr, Countryman JK, Leddy JP. J Immunol. 1980 Nov; 125(5):2063-8.
Review Interactions of complement with the red-cell membrane. [Semin Hematol. 1979]
Review Interactions of complement with the red-cell membrane.
Rosse WF. Semin Hematol. 1979 Apr; 16(2):128-39.
Review The properdin pathway: mechanisms of complement activation and analogies to the classical pathway. [Rheumatology. 1975]
Review The properdin pathway: mechanisms of complement activation and analogies to the classical pathway.
Fearon DT, Austen KF, Ruddy S. Rheumatology. 1975; 6:2-16.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

The hemolytic equivalence of human, guinea pig and canine complement proteins.
The hemolytic equivalence of human, guinea pig and canine complement proteins.
Immunol Commun. 1980 ;9(5):453-63.

PubMed
Social learning theory of aggression.
Social learning theory of aggression.
J Commun. 1978 Summer ;28(3):12-29.

PubMed
Caffeine and schizophrenia.
Caffeine and schizophrenia.
J Clin Psychiatry. 1978 Sep ;39(9):732-6.

PubMed
A novel rapid and continuous method for the resolution of cell dispersal activit...
A novel rapid and continuous method for the resolution of cell dispersal activities in crude trypsin preparations.
Dev Biol Stand. 1980 ;46:67-74.

PubMed
Protein-losing enteropathy secondary to intestinal lymphangiectasia in a dog.
Protein-losing enteropathy secondary to intestinal lymphangiectasia in a dog.
J Am Vet Med Assoc. 1978 Aug 1 ;173(3):271-4.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

The hemolytic equivalence of human, guinea pig and canine complement proteins.

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Supplemental Content

Save items

Related citations in PubMed

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information