J Clin Psychiatry. 1978 Sep;39(9):732-6.

Caffeine and schizophrenia.

Abstract

Two cases are described in which markedly increased consumption of caffeine led to an exacerbation of a schizophrenic process. The original description of this phenomenon and the clinical and basic science literature regarding the psychotropic effects of caffeine are reviewed. The cases are discussed in light of the clinical and research implications.

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