Abstract
Phosphorylation of the 20,000-dalton light chain of myosin is closely correlated with cross-bridge cycling in arterial smooth muscle. Evidence is presented that dephosphorylation can produce an attached, noncycling cross-bridge (latch-bridge) which is responsible for the high economy of force maintenance in this tissue.
MeSH terms
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Actins / metabolism*
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Animals
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Calcium / physiology
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Carotid Arteries / physiology*
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Macromolecular Substances
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Muscle Contraction*
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Muscle, Smooth / physiology*
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Myosins / metabolism*
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Phosphorylation
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Protein Kinases / metabolism
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Swine
Substances
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Actins
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Macromolecular Substances
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Protein Kinases
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Myosins
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Calcium