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Minimum inhibitory (MIC) and minimal lethal (MLC) concentrations of 30 antimicrobial agents were determined for field strains and for the A22 EAE vaccine strain of Chlamydia psittaci (ovis). No differences in susceptibility could be detected between strains. The antimicrobials could be divided into four groups. Group A had no effect on growth and development, Group B were bacteriostatic at concentrations in excess of 100 mg/l, Group C were bacteriostatic at concentrations of 10 mg/l or less but were bactericidal at concentrations above 10 mg/l and Group D were bactericidal at concentrations above 0.5 mg/l. The value of antimicrobials in aiding diagnosis and in the therapy of chlamydial abortion of ewes is discussed.
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