Your browser version may not work well with NCBI's Web applications. More information here...
1: Science. 1983 Jun 3;220(4601):1059-61.Click here to read Links

Neural crest cells contribute to normal aorticopulmonary septation.

By analyzing the hearts of quail-chick chimeras, it was found that neural crest cells at the level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum. Bilateral removal of this neural crest population prior to migration causes malformation of the aorticopulmonary septum resulting in common arterial outflow channels or transposition of the great vessels.

PMID: 6844926 [PubMed - indexed for MEDLINE]