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Clin Pediatr (Phila). 1981 Jul;20(7):475-8.

Ocular manifestations of the fetal hydantoin syndrome.

Abstract

Eleven per cent of infants exposed to hydantoins in utero have a recognizable pattern of abnormalities with serious clinical consequences. This report of a child born to a mother taking diphenylhydantoin emphasized the ocular findings. At birth and subsequent 8-month exam, a girl was noted to have microphthalmus, prominent iris vessels, and an inferior iris and choroidal colobma. Relation of these anomalies to teratogenic properties of diphenylhydantoin is discussed.

PMID:
6786811
[PubMed - indexed for MEDLINE]
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