Format

Send to:

Choose Destination
See comment in PubMed Commons below
Science. 1984 Aug 3;225(4661):478-82.

Endogenous ionic currents traverse intact and damaged bone.

Abstract

Living bone drives an electric current through itself and into sites of damage. Such "fracture currents" consist of two components: an intense, decaying current dependent on bone deformation and a stable, persistent current driven by a cellular battery. The latter is carried by chloride ions and, to a lesser extent, by sodium, magnesium, and calcium ions. Endogenous fracture currents are of the same polarity and similar magnitude as clinically applied currents that are successful in treating chronic nonunions in fractured bones. This suggests that the defect in biological nonunions may reside in the electrophysiology of repair.

PMID:
6740320
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk