Elevated glucose levels influence in vitro hatching, attachment, trophoblast outgrowth and differentiation of the mouse blastocyst

R J Wordinger; J A Kell

doi:10.1007/BF01939680

Elevated glucose levels influence in vitro hatching, attachment, trophoblast outgrowth and differentiation of the mouse blastocyst

Experientia. 1978 Jul 15;34(7):881-2. doi: 10.1007/BF01939680.

Authors

R J Wordinger, J A Kell

PMID: 668859
DOI: 10.1007/BF01939680

Abstract

A glucose concentration of 3.5 mg/ml is optimal for in vitro embryo attachment and trophoblastic cell outgrowth. Raising the concentration above 3.5 mg/ml does not improve embryo culture and can at certain concentrations be detrimental to embryo development.

MeSH terms

Animals
Blastocyst / drug effects*
Blastocyst / physiology
Cell Differentiation / drug effects
Culture Media
Embryo, Mammalian / drug effects
Embryo, Mammalian / physiology
Glucose / pharmacology*
Glucose / physiology
Mice
Organ Culture Techniques
Trophoblasts / physiology

Substances

Culture Media
Glucose