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Somat Cell Mol Genet. 1984 Mar;10(2):205-10.

Regional assignment of human amylase (AMY) to p22----p21 of chromosome 1.


A human genomic DNA segment (lambda hal) which hybridizes with rat pancreatic amylase cDNA was used to regionally assign amylase genes in human-mouse somatic cell hybrids. The assignment of amylase genes to chromosome 1 was confirmed and regionally mapped to the short arm region p22.1----p21 using a cell hybrid retaining a translocation involving chromosome 1 [46,XX,t(1;2)(p21;q37)]. Restriction length polymorphisms at the amylase loci are reported for gene linkage studies.

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