A 61-year-old housewife was diagnosed as having peptic ulcer disease for a period of 2 years. During this time she had episodes of abdominal cramping, dyspepsia, and one episode of severe upper gastrointestinal bleeding. She was subsequently found to have a large gastric lipoma. Gastric lipoma, a rare tumor, frequently mimics peptic ulcer disease in its clinical presentation and its complications. This point has not been previously emphasized.