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Biol Psychiatry. 1984 Feb;19(2):121-9.

Schizophrenic disorders and HLA-DR antigens.

Abstract

HLA-A, -B, and -DR antigens, including supertypic specificities (MT antigens), were studied in Japanese schizophrenic patients. Although frequencies of HLA-A, -B, and MT antigens did not differ significantly between the schizophrenic patients and controls, the frequency of DRw8 in DR locus showed a statistically significant increase in the patients. The authors conclude that DRw8 is a genetic marker of susceptibility to schizophrenia. Inconsistencies in previous reports of antigens could be resolved by examination of the DR locus.

PMID:
6585231
[PubMed - indexed for MEDLINE]
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