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Ann Hum Genet. 1984 Oct;48(Pt 4):333-45.

A computer program for constructing a maximum-likelihood map from linkage data and its application to human chromosome 1.

Abstract

An algorithm is described which attempts to find the maximum likelihood order of the loci on a chromosome using linkage data. It can also use data on locus order if these are available. A computer program which applies this algorithm has been written, and tested on the data for human chromosome 1. The most likely possible order is GDH, PGD, ENO1, Rh, UMPK, Sc, PGM1, AMY, Fy, CAE, 1qh, CMT1, AT3, PEPC.

PMID:
6548618
[PubMed - indexed for MEDLINE]
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