Cytogenet Cell Genet. 1984;38(1):76-9.

Localization of the human glucagon gene (GCG) to chromosome segment 2q36----37.

Schroeder WT, Lopez LC, Harper ME, Saunders GF.

Abstract

Hybridization of a 3H-labeled bovine glucagon cDNA plasmid to human metaphase chromosomes revealed significant labeling of the distal portion of the long arm of chromosome 2. A large portion (37%) of the cells analyzed exhibited labeling of the 2. A significant percentage (40%) of the labeled sites on the 2 were in segment 2q36----37. Therefore, the human glucagon gene (GCG), was assigned to this segment. Localization of the glucagon gene, whose chromosomal assignment was previously not known, demonstrates the general applicability of in situ hybridization as a powerful gene mapping technique.

PMID:: 6546710; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Chromosomal localization of the human alpha 1-antitrypsin gene (PI) to 14q31-32. [Am J Hum Genet. 1985]
Chromosomal localization of the human alpha 1-antitrypsin gene (PI) to 14q31-32.
Schroeder WT, Miller MF, Woo SL, Saunders GF. Am J Hum Genet. 1985 Sep; 37(5):868-72.
A major human histone gene cluster on the long arm of chromosome 1. [Science. 1984]
A major human histone gene cluster on the long arm of chromosome 1.
Green L, Van Antwerpen R, Stein J, Stein G, Tripputi P, Emanuel B, Selden J, Croce C. Science. 1984 Nov 16; 226(4676):838-40.
Localization of the thyroglobulin gene by in situ hybridization to human chromosomes. [Hum Genet. 1985]
Localization of the thyroglobulin gene by in situ hybridization to human chromosomes.
Bergé-Lefranc JL, Cartouzou G, Mattéi MG, Passage E, Malezet-Desmoulins C, Lissitzky S. Hum Genet. 1985; 69(1):28-31.
Review Down syndrome--a gene dosage disease caused by trisomy of genes within a small segment of the long arm of chromosome 21, exemplified by the study of effects from the superoxide-dismutase type 1 (SOD-1) gene. [APMIS Suppl. 1993]
Review Down syndrome--a gene dosage disease caused by trisomy of genes within a small segment of the long arm of chromosome 21, exemplified by the study of effects from the superoxide-dismutase type 1 (SOD-1) gene.
Annerén G, Edman B. APMIS Suppl. 1993; 40:71-9.
Review Duncan Guthrie Institute of Medical Genetics, Glasgow, University of Glasgow, Scotland. [Birth Defects Orig Artic Ser. ...]
Review Duncan Guthrie Institute of Medical Genetics, Glasgow, University of Glasgow, Scotland.
Ferguson-Smith MA, Aitken DA. Birth Defects Orig Artic Ser. 1982; 18(2):24-42.

See reviews... See all...

Cited by 4 PubMed Central articles

Structure of the human glucagon gene. [Nucleic Acids Res. 1986]
Structure of the human glucagon gene.
White JW, Saunders GF. Nucleic Acids Res. 1986 Jun 25; 14(12):4719-30.
A highly polymorphic locus in human DNA revealed by probes from cosmid 1-5 maps to chromosome 2q35----37. [Am J Hum Genet. 1986]
A highly polymorphic locus in human DNA revealed by probes from cosmid 1-5 maps to chromosome 2q35----37.
Litt M, Bruns GA, Sheehy R, Magenis RE. Am J Hum Genet. 1986 Mar; 38(3):288-96.
Dinucleotide repeat polymorphism in the human glucagon gene (GCG). [Nucleic Acids Res. 1991]
Dinucleotide repeat polymorphism in the human glucagon gene (GCG).
Wu S, Xiang K, Bell GI. Nucleic Acids Res. 1991 Mar 11; 19(5):1163.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide
Primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Localization of the human glucagon gene (GCG) to chromosome segment 2q36----37.
Localization of the human glucagon gene (GCG) to chromosome segment 2q36----37.
Cytogenet Cell Genet. 1984 ;38(1):76-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Localization of the human glucagon gene (GCG) to chromosome segment 2q36----37.

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Other Literature Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 4 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information