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Appl Environ Microbiol. 1984 Jan;47(1):98-100.

Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem C from Aspergillus terreus.

Abstract

Territrem C, a new tremorgenic mycotoxin (C28H32O9; molecular weight, 512.20) was isolated from the chloroform extract of rice cultures of Aspergillus terreus 23-1, which also produces territrems A and B. Isolation, acute toxicity, and some physicochemical properties of territrem C are discussed in this paper. The spectral and chemical evidence indicated that the structural difference between territrem C and territrem B (C29H34O9) was in their phenyl moieties: a 4-hydroxy-3,5-dimethoxy phenyl group in territrem C and a 3,4,5-trimethoxy phenyl group in territrem B. It was also demonstrated that territrem B was obtained by methylation of territrem C with dimethyl sulfate.

PMID:
6546485
[PubMed - indexed for MEDLINE]
PMCID:
PMC239619
Free PMC Article
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