Cephabacins, new cephem antibiotics of bacterial o...[J Antibiot (Tokyo). 1984]

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1: J Antibiot (Tokyo). 1984 Dec;37(12):1528-35.Links

Cephabacins, new cephem antibiotics of bacterial origin. I. Discovery and taxonomy of the producing organisms and fermentation.

Ono H, Nozaki Y, Katayama N, Okazaki H.

Three Gram-negative bacteria produce new cephem antibiotics, named cephabacins, with unique 3-side chains. Cephabacins include F group antibiotics with a 7-formylamino substituent and H group antibiotics without the substituent. The producing bacteria were taxonomically characterized and designated as Lysobacter lactamgenus sp. nov. YK-90 and Xanthomonas lactamgena sp. nov. YK-278 and YK-280.

PMID: 6526722 [PubMed - indexed for MEDLINE]

Cephabacins, new cephem antibiotics of bacterial origin. II. Isolation and characterization.
J Antibiot (Tokyo). 1984 Dec; 37(12):1536-45.

[J Antibiot (Tokyo). 1984]
Cephabacin M1-6, new 7-methoxycephem antibiotics of bacterial origin. I. A producing organism, fermentation, biological activities, and mode of action.
J Antibiot (Tokyo). 1985 Sep; 38(9):1141-51.

[J Antibiot (Tokyo). 1985]
Biosynthetic pathway of cephabacins in Lysobacter lactamgenus: molecular and biochemical characterization of the upstream region of the gene clusters for engineering of novel antibiotics.
Metab Eng. 2001 Oct; 3(4):380-92.

[Metab Eng. 2001]
ReviewEvolution of beta-lactam biosynthesis genes and recruitment of trans-acting factors.
Phytochemistry. 2005 Jun; 66(11):1200-10.

[Phytochemistry. 2005]
Review[Research and development of new oral cephems, cefixime and cefdinir]
Yakugaku Zasshi. 1993 Sep; 113(9):605-26.

[Yakugaku Zasshi. 1993]
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Cited by 1 PubMed Central article

Beta-lactam biosynthesis in a gram-negative eubacterium: purification and characterization of isopenicillin N synthase from Flavobacterium sp. strain SC 12.154.
Palissa H, von Döhren H, Kleinkauf H, Ting HH, Baldwin JE. J Bacteriol. 1989 Oct; 171(10):5720-8.

[J Bacteriol. 1989]

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