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    Boll Soc Ital Biol Sper. 1984 Sep 30;60(9):1709-14.

    [Effect of sex steroids in vivo and in vitro on the binding of uric acid to plasma proteins].

    [Article in Italian]

    Abstract

    Modifications on the binding of uric acid to human plasma proteins have been studied in regularly menstruating females aged 25-30 years with a normal cycle, in comparison with a group of healthy age-matched males and with a group of post-menopausal females. The binding of uric acid to plasma proteins was estimated using micropartition system Amicon. The results obtained demonstrate a significant increase of uric acid binding during ovulatory and mid-luteal phase of menstrual cycle. No modifications are shown in post-menopausal females and in healthy males. No modifications have been shown with the same experiments performed in vitro.

    PMID:
    6525290
    [PubMed - indexed for MEDLINE]

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