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A new rating scale for Alzheimer's disease.
A new rating instrument, the Alzheimer's Disease Assessment Scale, was designed specifically to evaluate the severity of cognitive and noncognitive behavioral dysfunctions characteristic of persons with Alzheimer's disease. Item descriptions, administration procedures, and scoring are outlined. Twenty-seven subjects with Alzheimer's disease and 28 normal elderly subjects were rated on 40 items. Twenty-one items with significant intraclass correlation coefficients for interrater reliability (range, .650-.989) and significant Spearman rank-order correlation coefficients for test-retest reliability (range, .514-1) constitute the final scale. Subjects with Alzheimer's disease had significantly more cognitive and noncognitive dysfunction than the normal elderly subjects.
PMID: 6496779 [PubMed - indexed for MEDLINE]
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Cited by 54 PubMed Central articles
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Update on the use of memantine in Alzheimer's disease.
van Marum RJ.
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[Neuropsychiatr Dis Treat. 2009]
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Lleó A.
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[Curr Genomics. 2007]
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Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.
Kolstoe SE, Ridha BH, Bellotti V, Wang N, Robinson CV, Crutch SJ, Keir G, Kukkastenvehmas R, Gallimore JR, Hutchinson WL, et al.
Proc Natl Acad Sci U S A. 2009 May 5; 106(18):7619-23. Epub 2009 Apr 16.
[Proc Natl Acad Sci U S A. 2009]
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