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Antacid-induced osteomalacia and nephrolithiasis.
A 36-year-old woman suffered from bone pain, muscle weakness, and renal stones after prolonged ingestion of antacids for esophageal reflux. Investigation disclosed hypophosphatemia, hypercalciuria, and osteomalacia by bone biopsy. All symptoms and abnormal laboratory findings reversed with a regimen of oral phosphate supplementation and cessation of antacid intake.
PMID: 646554 [PubMed - indexed for MEDLINE]
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Cited by 1 PubMed Central article
Patient Drug Information
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Aluminum Hydroxide (AlternaGEL® , Alu-Cap® , Alu-Tab® , ...)
Aluminum hydroxide is used for the relief of heartburn, sour stomach, and peptic ulcer pain and to promote the healing of peptic ulcers.
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Magnesium Hydroxide (Milk of Magnesia® , Milk of Magnesia-Concentrated® , Phillips Milk of Magnesia® )
Magnesium hydroxide is used on a short-term basis to treat constipation.
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Aluminum Hydroxide and Magnesium Hydroxide (Alamag® , Maalox® , Mag-Al® , ...)
Aluminum hydroxide and magnesium hydroxide are antacids used together to relieve heartburn, acid indigestion, and stomach upset. They may be used to treat these symptoms in patients with peptic ulcer, gastritis, esophagi...