Antacid-induced osteomalacia and nephrolithiasis. [Arch Intern Med. 1978]

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1: Arch Intern Med. 1978 Jun;138(6):1007-9.Links

Antacid-induced osteomalacia and nephrolithiasis.

Cooke N, Teitelbaum S, Avioli LV.

A 36-year-old woman suffered from bone pain, muscle weakness, and renal stones after prolonged ingestion of antacids for esophageal reflux. Investigation disclosed hypophosphatemia, hypercalciuria, and osteomalacia by bone biopsy. All symptoms and abnormal laboratory findings reversed with a regimen of oral phosphate supplementation and cessation of antacid intake.

PMID: 646554 [PubMed - indexed for MEDLINE]

Antacid and sucralfate-induced hypophosphatemic osteomalacia: a case report and review of the literature. [Calcif Tissue Int. 1990]
Osteomalacia from Al and Mg antacids. Report of a case of bilateral hip fracture. [Acta Orthop Scand. 1989]
An interesting case of osteomalacia due to antacid use associated with stainable bone aluminum in a patient with normal renal function. [Bone. 1998]
Osteomalacia and weakness from excessive antacid ingestion. [JAMA. 1980]
Antacid-induced osteomalacia. [Cleve Clin J Med. 1987]
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Antacid-induced osteomalacia and nephrolithiasis.

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