Ann Rheum Dis. 1978 Apr;37(2):164-7.

Impairment of lachrymal and salivary secretion and cellular immune responses to salivary antigens in rheumatoid arthritis.

Sullivan S, Fernandes L, McFarlane IG, Wojcicka B, Eddleston AL, Doniach D, Hamilton E, Williams R.

Abstract

During a systematic investigation of 100 unselected outpatients with rheumatoid arthritis, 58 were found to have reduced lachrymal or salivary secretion. No correlation could be detected between the presence or absence of secretory abnormalities and the age or sex of the patient, the presence of nodules or salivary duct antibody, or the occurrence of vasculitis. However, there was a significant correlation between diminished salivary of lachrymal flow and the occurrence of cellular immune responses to a protein fraction of normal human saliva, sensitisation being found in 94% of those with impairment of salivary and lachrymal secretion as compared with 33% of those without.

PMID:: 646468; [PubMed - indexed for MEDLINE]
PMCID:: PMC1001183

Free PMC Article

MeSH Terms, Substances

MeSH Terms

Substances

Antibodies

LinkOut - more resources

Full Text Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Clinical and immunological factors associated with low lacrimal and salivary flow rate in patients with primary Sjögren's syndrome. [J Rheumatol. 2002]
Clinical and immunological factors associated with low lacrimal and salivary flow rate in patients with primary Sjögren's syndrome.
Haga HJ. J Rheumatol. 2002 Feb; 29(2):305-8.
Salivary secretion and connective tissue disease in man. [Ann Rheum Dis. 1985]
Salivary secretion and connective tissue disease in man.
Matthews RW, Bhoola KD, Rasker JJ, Jayson MI. Ann Rheum Dis. 1985 Jan; 44(1):20-6.
Focal sialadenitis in patients with ankylosing spondylitis and spondyloarthropathy: a comparison with patients with rheumatoid arthritis or mixed connective tissue disease. [Ann Rheum Dis. 2001]
Focal sialadenitis in patients with ankylosing spondylitis and spondyloarthropathy: a comparison with patients with rheumatoid arthritis or mixed connective tissue disease.
Helenius LM, Hietanen JH, Helenius I, Kautiainen H, Piirainen H, Paimela L, Lappalainen M, Suuronen R, Lindqvist C, Leirisalo-Repo M. Ann Rheum Dis. 2001 Aug; 60(8):744-9.
Review Duct-associated lymphoid tissue (DALT) of minor salivary glands and mucosal immunity. [Immunology. 1986]
Review Duct-associated lymphoid tissue (DALT) of minor salivary glands and mucosal immunity.
Nair PN, Schroeder HE. Immunology. 1986 Feb; 57(2):171-80.
Review Effect of photic stimuli on rat salivary glands. Role of sympathetic nervous system. [Acta Odontol Latinoam. 2000]
Review Effect of photic stimuli on rat salivary glands. Role of sympathetic nervous system.
Bellavía S, Gallará R. Acta Odontol Latinoam. 2000; 13(1):3-19.

See reviews... See all...

Cited by 4 PubMed Central articles

Salivary antioxidants and metalloproteinases in juvenile idiopathic arthritis. [Mol Med. 2010]
Salivary antioxidants and metalloproteinases in juvenile idiopathic arthritis.
Brik R, Rosen I, Savulescu D, Borovoi I, Gavish M, Nagler R. Mol Med. 2010 Mar; 16(3-4):122-8. Epub 2009 Dec 28.
Increased C1q binding and arthritis in primary biliary cirrhosis. [Gut. 1980]
Increased C1q binding and arthritis in primary biliary cirrhosis.
Crowe JP, Molloy MG, Wells I, Thompson BR, Holborow EJ, Hamilton E, Williams R. Gut. 1980 May; 21(5):418-22.
Review Clinical associations between arthritis and liver disease. [Ann Rheum Dis. 1982]
Review Clinical associations between arthritis and liver disease.
Mills PR, Sturrock RD. Ann Rheum Dis. 1982 Jun; 41(3):295-307.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Impairment of lachrymal and salivary secretion and cellular immune responses to ...
Impairment of lachrymal and salivary secretion and cellular immune responses to salivary antigens in rheumatoid arthritis.
Ann Rheum Dis. 1978 Apr ;37(2):164-7.

PubMed
The pilot Stroke Data Bank: definition, design, and data.
The pilot Stroke Data Bank: definition, design, and data.
Stroke. 1984 Jul-Aug ;15(4):740-6.

PubMed
Origin of familial malignant melanomas from heritable melanocytic lesions. 'The ...
Origin of familial malignant melanomas from heritable melanocytic lesions. 'The B-K mole syndrome'.
Arch Dermatol. 1978 May ;114(5):732-8.

PubMed
Suprascapular nerve compression syndrome.
Suprascapular nerve compression syndrome.
Surg Neurol. 1984 Sep ;22(3):308-12.

PubMed
[Behavior and mental activity disorders after carbon monoxide poisoning. Bilater...
[Behavior and mental activity disorders after carbon monoxide poisoning. Bilateral pallidal lesions].
Rev Neurol (Paris). 1984 ;140(6-7):401-5.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: