J Affect Disord. 1981 Jun;3(2):193-202.

Bromocriptine and imipramine in endogenous depression. A double-blind controlled trial in out-patients.

Abstract

Among 33 out-patients with endogenous depression, 16 were treated with bromocriptine (10-60 mg/day, mean 34) and 17 with imipramine (75-250 mg/day, mean 143). The total score on the Hamilton Rating Scale decreased during 6-week treatment from 19.9 to 7.8 in the bromocriptine group (P less than 0.001) and from 20.1 to 6.1 in the imipramine group (P less than 0.001). There was no significant difference between the two groups. The main side-effects were for bromocriptine: nausea, dizziness, and headache; for imipramine; dryness of mouth, dizziness, and sweating. This study suggests an antidepressant effect of bromocriptine although, due to the possibility of Type II error, it may not necessarily be equal to that of imipramine.

PMID:: 6454713; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Molecular Biology Databases

IMIPRAMINE - HSDB

Supplemental Content

Save items

Related citations in PubMed

Bromocriptine in depression. [Curr Med Res Opin. 1982]
Bromocriptine in depression.
Bouras N, Bridges PK. Curr Med Res Opin. 1982; 8(3):150-3.
Multicenter double-blind comparison of nomifensine and imipramine for efficacy and safety in depressed outpatients. [J Clin Psychiatry. 1984]
Multicenter double-blind comparison of nomifensine and imipramine for efficacy and safety in depressed outpatients.
Bremner JD, Abrahams LM, Crupie JE, McCawley A, Proctor RC, Sathananthan GL. J Clin Psychiatry. 1984 Apr; 45(4 Pt 2):56-9.
Fluvoxamine maleate in the treatment of depression: a single-center, double-blind, placebo-controlled comparison with imipramine in outpatients. [J Clin Psychopharmacol. 1996]
Fluvoxamine maleate in the treatment of depression: a single-center, double-blind, placebo-controlled comparison with imipramine in outpatients.
Claghorn JL, Earl CQ, Walczak DD, Stoner KA, Wong LF, Kanter D, Houser VP. J Clin Psychopharmacol. 1996 Apr; 16(2):113-20.
Review A controlled trial of amitriptyline and cianopramine in major depression. [Clin Ther. 1985]
Review A controlled trial of amitriptyline and cianopramine in major depression.
Mellsop GW, Burgess CD, Vijayasenan ME. Clin Ther. 1985; 7(6):699-703.
Review Spotlight on sertraline in the management of major depressive disorder in elderly patients. [CNS Drugs. 2002]
Review Spotlight on sertraline in the management of major depressive disorder in elderly patients.
Muijsers RB, Plosker GL, Noble S. CNS Drugs. 2002; 16(11):789-94.

See reviews... See all...

Cited by 3 PubMed Central articles

Long-term administration of the dopamine D3/2 receptor agonist pramipexole increases dopamine and serotonin neurotransmission in the male rat forebrain. [J Psychiatry Neurosci. 2012]
Long-term administration of the dopamine D3/2 receptor agonist pramipexole increases dopamine and serotonin neurotransmission in the male rat forebrain.
Chernoloz O, El Mansari M, Blier P. J Psychiatry Neurosci. 2012 Feb; 37(2):113-21.
Review Reconsidering anhedonia in depression: lessons from translational neuroscience. [Neurosci Biobehav Rev. 2011]
Review Reconsidering anhedonia in depression: lessons from translational neuroscience.
Treadway MT, Zald DH. Neurosci Biobehav Rev. 2011 Jan; 35(3):537-55. Epub 2010 Jul 11.
The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression. [Neuropsychopharmacology. 2005]
The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression.
Roiser JP, McLean A, Ogilvie AD, Blackwell AD, Bamber DJ, Goodyer I, Jones PB, Sahakian BJ. Neuropsychopharmacology. 2005 Apr; 30(4):775-85.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Bromocriptine and imipramine in endogenous depression. A double-blind controlled...
Bromocriptine and imipramine in endogenous depression. A double-blind controlled trial in out-patients.
J Affect Disord. 1981 Jun ;3(2):193-202.

PubMed
The ovary after menopause.
The ovary after menopause.
Clin Obstet Gynecol. 1981 Mar ;24(1):181-91.

PubMed
Developing a curriculum for an MPH degree in health education for Africa--how su...
Developing a curriculum for an MPH degree in health education for Africa--how suitable are the US models?
Int J Health Educ. 1978 Jan-Mar ;21 Suppl 1:2-24.

PubMed
The molecular genetics of human hemoglobins.
The molecular genetics of human hemoglobins.
Annu Rev Genet. 1980 ;14:145-78.

PubMed
Inherited erythrocyte phosphofructokinase deficiency: molecular mechanism.
Inherited erythrocyte phosphofructokinase deficiency: molecular mechanism.
Hum Genet. 1980 ;55(3):383-90.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Bromocriptine and imipramine in endogenous depression. A double-blind controlled trial in out-patients.

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information