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    J Inherit Metab Dis. 1984;7(4):155-6.

    beta-Mannosidase in human leukocytes and fibroblasts.

    Panday RS, van Diggelen OP, Kleijer WJ, Niermeijer MF.

    In human leukocytes and fibroblasts beta-mannosidase activity has a unimodal pH optimum (4.0-4.5). Markedly reduced activity is found in I-cell disease. Normal activities in human fibroblasts are ten times higher than in the goat, in which species a deficiency disease has been described.

    PMID: 6441861 [PubMed - indexed for MEDLINE]

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