Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Aust J Exp Biol Med Sci. 1984 Jun;62 ( Pt 3):317-23.

On the possible role of prostaglandin E2 in intestinal stasis in the gastric brooding frog Rheobatrachus silus.

Abstract

Responses of isolated intestinal preparations from the anurans Bufo marinus and Limnodynastes tasmaniensis to various agents have been studied, as models for the intestinal stasis reported in the rare gastric brooding frog, Rheobatrachus silus. It is inferred from the responses that the preparations possessed excitatory muscarinic and histamine receptors and inhibitory adrenergic receptors, conforming to the typical vertebrate pattern. The circular muscle was unresponsive to prostaglandin E2, whereas longitudinal muscle relaxed to prostaglandin E2. Some of the longitudinal preparations exhibited a biphasic response to arachidonic acid, i.e. contraction followed by relaxation. Indomethacin prevented the relaxation phase, indicating that the intestine synthesised a prostaglandin E-like substance from arachidonic acid. These results draw attention to the possibility that PGE2 may be responsible for the intestinal stasis associated with gastric brooding in the gastric brooding frog.

PMID:
6437385
[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk